Abstract
Silver nanoparticles (AgNP) have been already proposed for many advanced research approaches in the fields of therapeutics and nanomedicine due to their non-antigenicity and more potent optical characteristics along with their respective antioxidant and antimicrobial properties in effective site specific targeted drug-delivery practices systems. In last few years, chemically synthesized metal based nanoparticles has been studies for their biological and delivery behaviours because of use of various chemical and bio-hazardous chemicals in their preparations. Various previous studies on green synthesis of silver metal based nanoparticles have been designed which involved biological sources like microorganisms, plants and herbal extracts as cost effective, eco-friendly and non-toxic approaches. So that, green synthesis of silver nanoparticles has been much exploited in wider range of applications in the field of biomedical, therapeutics, nanomedicine and pharmaceuticals as more potent and safe drug delivery vehicles as compared to chemically preparations of silver nanoparticles. Therefore, in this review, we recollected the comparative studies based on advantages of green approaches of silver nanoparticles over their respective chemical preparations. Keywords: Silver nanoparticles, Green synthesis, Therapeutics, Nanomedicine, Drug delivery vehicles.
Highlights
These days, bionanotechnology and nanomedicine are considered major thrust areas for clinical and pharmaceutical application because of using various metals or metal based conjugates which in turn, have excellent optical, chemical and biological properties.[1]
More advanced green approach have been considered for preparing silver nanoparticle as biological reducing, free radical scavenging and capping agents which found to reduce Ag+ to Ag0.8 a broad range of various biological agents are considered for rapid, safe and green synthesis of silver nanoparticles by using bacteria, fungi/plant extracts, yeast and secondary metabolites.[9,10]
Green synthesis by using Fungi Fungal species have been widely used for synthesis of silver nanoparticles in the range of 4-90nm because of their ability to secrete large quantities of proteins, enzymes and extracellular secondary metabolites which results in rapid bio-reduction of dissolved silver salts resulted in extracellular synthesis.[34,35]
Summary
These days, bionanotechnology and nanomedicine are considered major thrust areas for clinical and pharmaceutical application because of using various metals or metal based conjugates which in turn, have excellent optical, chemical and biological properties.[1].
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