Abstract

Background Evidences which prove relation between breastfeeding women and risk of breast cancer have been limited. Objective A meta-analysis was carried out on the basis of published literature from clinical trials and studies among different parts of the world. Methods Studies were analyzed and extracted using PRISMA flowchart. RevMan 5.4.1 was used for analyzing the extracted data. Included studies were fully cited texts with complete information about studies, trails conducted for risk of breast cancer, and breastfeeding correlations. Results Menarche age, family history, lactation duration, and menopausal status have a strong effect on the risks of breast cancer. Family history studies concluded that for 95% CI, the risk ratio was 2.66 (2.00, 3.52). Conclusion Findings have suggested that family history and lactation duration affect the risks of breast cancer.

Highlights

  • According to the World Cancer Research Fund and American Institute for Cancer Research report from 2007, women’s health is benefited from breastfeeding (BF)

  • The initial frail confirmation of breast cancer incidence is observed by the ecological relationship between the observed trends and the depreciation of breastfeeding among women in different parts of the world

  • Our literature search strategy is presented in Figure 1; the studies considered for this metaanalysis was performed considering the observational studies in epidemiology (MOOSE) and preferred items for systematic reviews and meta-analysis (PRISMA)

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Summary

Introduction

Other risk factors documented are lower age during menstruation, i.e., less than 10 years; delay in maternal age as first full-time pregnancy (around 30-40 years); and limited periods of breastfeeding [2, 3] These studies suggest a strong link between breastfeeding and breast cancer. The initial frail confirmation of breast cancer incidence is observed by the ecological relationship between the observed trends and the depreciation of breastfeeding among women in different parts of the world. Another indirect trail of science is taken from the early observation of the association between breastfeeding and the delayed return of the period of ovulation throughout the postpartum. Findings have suggested that family history and lactation duration affect the risks of breast cancer

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