Abstract
Breast milk cell culture supernatants from atopic mothers (nineteen) were compared by ELISA with normal breast-feeding controls (twenty-one) for regulation of cord blood lymphocyte IgA and IgE secretion in vitro. A minority of atopic (five out of nineteen) and normal (three out of twenty-one) cell supernatants stimulated cord blood lymphocyte IgA release to the same extent. The others were inactive. Stimulation was not related to breast milk cells donor atopic history or cord blood lymphocyte atopic heredity. In contrast, 70% of atopic milk cell supernatants stimulated cord blood lymphocyte cultures to form IgE (means +/- s.d. = 2070 +/- 2240 pg/culture) while stimulatory supernatants (24%) from normal donors resulted in less lymphocyte IgE release (means +/- s.d. = 680 +/- 490 pg/culture) (p less than 0.001). These differences did not correlate with breast milk cell supernatant IgE concentrations, cord blood donor serum IgE levels or atopic heredity.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
