Abstract
Abstract: Five cases of breast carcinomas arising in microglandular adenosis (MGA) are described. This type of carcinoma is rare and due to 5–100 protein positivity of the tumor cells might be misinterpreted as malignant melanoma, especially when poorly differentiated or displaying a prominent clear cell change. The distinct presence of MGA with transition through areas of atypical MGA around the carcinoma, and the cytokeratin positivity of tumor cells assist in establishing the correct diagnosis. This study also supports the observation that MGA may be associated with an increased risk for subsequent development of invasive carcinoma.
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