Breast cancer treatment planning using a novel spherical fuzzy CRITIC-REGIME

Abstract

Breast cancer is the leading cause of cancer-related deaths, and choosing a suitable treatment plan for this disease has proved difficult for oncologists owing to the variety of criteria and alternatives that must be considered during the decision-making process. Since prospective treatment options influence patients’ health-related quality of life in a variety of ways, a methodology that can completely and objectively evaluate alternative treatments has become an essential issue. This paper proposes a novel multi-criteria decision-making (MCDM) methodology by integrating the CRiteria Importance Through Intercriteria Correlation (CRITIC) and the REGIME techniques and handles the problem of breast cancer treatment selection problem. CRITIC enables the determination of objective criterion weights based on the decision matrix, while REGIME ranks the options without the need for lengthy computations or normalization procedures. The suggested methodology is demonstrated in a spherical fuzzy atmosphere, which allows decision experts to independently express their degrees of membership, non-membership, and hesitancy in a broad three-dimensional spherical space. In the numerical example provided, three oncologists evaluate four breast cancer treatment alternatives, namely, surgery, radiotherapy, chemotherapy, and hormone therapy, with respect to five criteria, which are disease or tumor type, stage of disease, patient type, side effects, and financial status of the patient. The tumor type is determined to be the most important assessment criterion, and surgery is selected as the best course of action. The stability and validity of the proposed methodology are verified through sensitivity and comparative studies. The discussions, limitations, and future research avenues are also given within the study.