Abstract
Breast cancer is the most common tumor and the main cause of death for malignancy in women. Common sites of metastasis include bones, lungs, lymph nodes, liver and brain. Although widespread metastases can compress or infiltrate the bile ducts, direct metastatic involvement of extrahepatic bile ducts are rare. Herein we present a patient with a history of breast cancer who is an exceptional case with metastatic infiltration of extrahepatic bile ducts in the absence of hepatic lesions and any other systemic metastasis.
Highlights
We report a case that was operated for breast cancer and admitted with obstructive jaundice after 14 months from completing adjuvant therapies and without any hepatic metastatic lesions
Popp et al report the largest series in the literature with seven cases of breast cancer patients who underwent surgery for obstructive jaundice caused by metastasis (6)
In this report; the etiology of jaundice in patients were reported as liver metastasis in two patients, compression of bile tract by enlarged lymph nodes in six patients and direct metastasis to the bile duct only in one patient
Summary
Breast cancer is the most common malignancy in women accounting 29% of all female tumors. At the time of diagnosis 10% of the breast cancer patients have distant metastasis. We report a case that was operated for breast cancer and admitted with obstructive jaundice after 14 months from completing adjuvant therapies and without any hepatic metastatic lesions. From her medical history we have learned that she had had an operation for right breast carcinoma 14 months ago. There had been 12 metastatic lymph nodes and the tumor was ER negative, PR negative and C-Erb B2 positive immunhistochemically She had adjuvant chemotherapy and radiotherapy and had been under follow-up since that time with no evidence of distant metastasis. The patient has been under chemotherapy treatment since recovery with multiple liver metastasis detected 4 months after the operation
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