Abstract

Breast cancer (BC) is the primary threat to women’s health, and early diagnosis of breast cancer is imperative. Although there are many ways to diagnose breast cancer, the gold standard is still pathological examination. In this paper, a low dimensional three-channel features based breast cancer histopathological images recognition method is proposed to achieve fast and accurate breast cancer benign and malignant recognition. Three-channel features of 10 descriptors were extracted, which are gray level co-occurrence matrix on one direction (GLCM1), gray level co-occurrence matrix on four directions (GLCM4), average pixel value of each channel (APVEC), Hu invariant moment (HIM), wavelet features, Tamura, completed local binary pattern (CLBP), local binary pattern (LBP), Gabor, histogram of oriented gradient (Hog), respectively. Then support vector machine (SVM) was used to assess their performance. Experiments on BreaKHis dataset show that GLCM1, GLCM4 and APVEC achieved the recognition accuracy of 90.2%-94.97% at the image level and 89.18%-94.24% at the patient level, which is better than many state-of-the-art methods, including many deep learning frameworks. The experimental results show that the breast cancer recognition based on high dimensional features will increase the recognition time, but the recognition accuracy is not greatly improved. Three-channel features will enhance the recognizability of the image, so as to achieve higher recognition accuracy than gray-level features.

Highlights

  • Cancer has become one of the major public health problems that seriously threaten the health of people

  • In order to show the effectiveness of low dimensional features, local binary pattern (LBP), Gabor, and histogram of oriented gradient (Hog) were introduced for comparison

  • A breast cancer histopathological images recognition method based on low dimensional three-channel features is proposed

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Summary

Introduction

Cancer has become one of the major public health problems that seriously threaten the health of people. Accurate diagnosis is the key to improve the survival rate of patients. Mammogram is the first step of early diagnosis, but it is difficult to detect cancer in the dense breast of adolescent women, and the X-ray radiation poses a threat to the health of patients and radiologists. The gold standard for breast cancer diagnosis is still pathological examination. Accurate diagnosis of breast cancer requires experienced histopathologists, and it requires a lot of time and effort to complete this task. The diagnosis results of different histopathologists are not the same, which strongly depends on the prior knowledge of histopathologists. It resulting in lower diagnosis consistency, and the average diagnosis accuracy is only 75% [1]

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