Breast and prostate cancer: an analysis of common epidemiological, genetic, and biochemical features.

Abstract

I. Introduction II. Epidemiological Evidence Associating Breast and Prostate Cancer III. Incidence of Breast and Prostate Cancer in Different Countries: Dietary Factors IV. Genetic Abnormalities Common to Breast and Prostate Cancer A. AR alterations in prostate cancer B. AR alterations in breast cancer C. BRCA1 and BRCA2 alterations in breast cancer D. BRCA1 and BRCA2 alterations in prostate cancer E. Other genes associated with breast or prostate cancer V. Common Biochemical Features of Breast and Prostate Cancer A. Prostate-specific antigen (PSA) B. Apolipoprotein D (apoD) C. Zn-α2-gp D. Gross cystic disease fluid protein-15 E. Pepsinogen C F. Other proteins VI. Growth Factors in Breast and Prostate Cancer A. AIGF B. KGF VII. Theories of Breast and Prostate Cancer Development: Role of Steroid Hormones VIII. Conclusions