Abstract
In medicine, nothing is more satisfying than witnessing the accumulation of knowledge through research efforts and the transformation of clinical practice that follows. Many colleagues from our generation remember the days when we struggled to care for patients with chronic viral hepatitis, with few therapies to offer and the inevitable deterioration in some patients over time. Fast forward to the present where chronic hepatitis C infection is eradicated with 8 to 12 weeks of direct-acting antivirals and essentially 100% of patients treated with entecavir or tenofovir for chronic hepatitis B achieve sustained viral suppression.
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