Abstract
We measured the contents of brain-derived neurotrophic factor (BDNF) in the lacrimal fluid, aqueous humor, and blood serum in 40 patients (40 eyes) with age-related cataracts. Collection of stimulated lacrimal fluid was performed by a pipette on the day preceding surgery; the aqueous humor and the blood were sampled during the phacoemulsification of a cataract. BDNF was measured using an enzyme immunoassay. On average, the concentration of BDNF in patients was 121.2 ± 47.7 pg/mL in the lacrimal fluid, 52.2 ± 25.7 pg/mL in the aqueous humor, and 23418 ± 7645 pg/mL in the blood serum. The concentration of BDNF in the aqueous humor correlated well with its content in the lacrimal fluid (Pearson’s correlation coefficient was 0.61, P < 0.000) and was below it by a factor of 0.44 ± 0.19 on average. The data we obtained may be used for an approximate evaluation of the BDNF concentration in the aqueous humor on the basis of an analysis of the lacrimal fluid.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
