Abstract

Inference of tumor and edema areas from brain magnetic resonance imaging (MRI) data remains challenging owing to the complex structure of brain tumors, blurred boundaries, and external factors such as noise. To alleviate noise sensitivity and improve the stability of segmentation, an effective hybrid clustering algorithm combined with morphological operations is proposed for segmenting brain tumors in this paper. The main contributions of the paper are as follows: firstly, adaptive Wiener filtering is utilized for denoising, and morphological operations are used for removing nonbrain tissue, effectively reducing the method's sensitivity to noise. Secondly, K-means++ clustering is combined with the Gaussian kernel-based fuzzy C-means algorithm to segment images. This clustering not only improves the algorithm's stability, but also reduces the sensitivity of clustering parameters. Finally, the extracted tumor images are postprocessed using morphological operations and median filtering to obtain accurate representations of brain tumors. In addition, the proposed algorithm was compared with other current segmentation algorithms. The results show that the proposed algorithm performs better in terms of accuracy, sensitivity, specificity, and recall.

Highlights

  • Brain tumor is one of the most serious diseases, which often have lethal outcomes

  • (iv) The proposed method is combined with morphological operations for preprocessing and postprocessing, which further improves the accuracy of segmentation

  • Morphological operations and median filtering are applied as postprocessing to obtain the final segmentation results

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Summary

Introduction

Brain tumor is one of the most serious diseases, which often have lethal outcomes. More and more attention has been paid to the study of brain tumor image. MRI is especially useful for brain imaging [1], which can be performed without injecting radioisotopes. MRI is based on multiparameter imaging, which can form different images by adjusting different parameters and contains a large amount of information. The FLAIR modalities are usually used for finding the extensions of tumors and edemas. We use segmentation of FLAIR images in BRATS 2012 [2]

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