Abstract

Brain tissue oxygen monitoring is a relatively new technique for continuous measurement of focal brain tissue oxygen tension (PbtO2). There are several studies of PbtO2monitoring in adult patients but few in children. The goal is the prevention, or early detection and treatment, of secondary insults. Episodes of low PbtO2are associated with worse outcome, and treatment directed by PbtO2may benefit patients, but there is no Class I evidence as yet. What determines PbtO2is multifactorial and the underlying pathophysiological events affecting PbtO2may be complex. The clinician using this technology must understand the technical and physiological aspects, as well as the limitations, of PbtO2monitoring if there is to be any clinical benefit. However, whether PbtO2monitoring delivers overall benefit across centers of different expertise requires a randomised controlled trial. This review examines the current literature on PbtO2monitoring with a focus on children, the important technical and physiological factors, and an approach to using a PbtO2monitor.

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