Abstract

Precise localization of anatomic structures within the brain is crucial to neurosurgeons. In this paper, we report our recent investigation of using a low-cost, miniaturized, optical reflectance (elastic) spectroscopy device to obtain, in real-time, brain structural mapping during stereotactic surgery for movement disorders. 20 subjects were studied with IRB approval during temporal lobectomy or stereotactic surgery. The Measurement results show that this instrument along with our developed algorithm allows us to distinguish white and gray matter with a resolution of 1 mm. The technique is extremely easy in practice, and the equipment is inexpensive, miniature, and provides real-time brain structural mapping and localization in the operating room.

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