Brain stimulation method and analysis of eeg seizure time series

Abstract

The aim of this research work is to develop keeping in mind the sweeping changes in Electro Convulsive Therapy (ECT). It is has been tried to inculcate these improvements to make the research work efficient and feasible. ECT is most effective treatment available to certain severe neurological disorders. Recent studies demonstrate association between certain parameters and methods of ECT seizure induction. There is evidence that the latter and therapeutic potency of ECT related. Seizure was obtained unilateral and bilateral application of electrical stimulus. An adequate seizure during ECT is still defined by its duration. Differing therapeutic potencies of ECT procedures cannot be explained on seizure duration alone; other parameter is spectral power in delta frequency band of EEG. This research work is to examine the clinical application of the findings to elucidate the therapeutic relevance of seizure measures other than seizure duration. The other measuring seizure parameters relevant therapeutic mechanism of ECT are power distribution, synchronization in various phases of EEG time series data collected during ECT and spectral power distribution in frequency bands of EEG. This research work involves several signal processing techniques: four channel EEG time series digital signal calibration, removing baseline drift, filtering processes to eliminate noise and artifacts, an automated selection of seizure phases. From the quantified EEG an empirical criterion for brain stimulus has been obtained.