Brain responses to high frequencies (270 Hz-480 Hz) changes due to vibratory stimulation of human fingertips: An fMRI study

Abstract

This fMRI study investigated the effects of vibratory stimulation on somatosensory areas during high-frequencies stimulation using a piezoelectric finger stimulation system during an fMRI scan. Twelve healthy right-handed subjects were stimulated at 270 Hz-480 Hz and the fMRI dataset was analysed to generate the activated regions due to the high-frequencies stimulation. The activated regions were identified and thresholded at Puncorrected<0.001 for multiple comparisons. The average effect of frequencies revealed significant activation in the left thalamus, right inferior parietal gyrus, right medial frontal gyrus, and right precuneus whereas the main effect of frequencies revealed significant activation in the left thalamus. The positive effect of frequencies displayed significant activation in the left pallidum, right amygdala, right superior temporal gyrus, right medial temporal gyrus. The vibratory stimulation at a frequency of 330 Hz and 360 Hz (330 Hz<360 Hz) revealed a significant difference in the left thalamus. Findings indicated the role of the secondary somatosensory areas processing and transporting sensory information to perform the perceptual and cognitive function.