Abstract
Nutrient signals called postingestive effects are thought to be the sixth sensory signals (gut feeling). They modulate motivation to eat and subsequent food preference. Although the other five senses are well-characterized, there are still a lot of mysteries in the processing of luminal nutrient information in the brain. Development of functional MRI (fMRI) technique during the past 10 years enabled researchers to investigate brain function for the detection, perception, and processing of chemosensory information in human beings. We developed an awake rat fMRI technique to investigate whole brain function for the detection of ingested nutrients. Here we will review a recent study of luminal nutrient information in humans and in rodents.
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