Abstract
To the Editor: The article by Henskens et al1 on brain microbleeds supports a view2 that cerebral microvascular disease in hypertensive patients is responsible for intellectual deterioration and is caused by abnormal flow pulsations extending into the small cerebral vessels as a consequence of aortic stiffening. The relationship between cognitive decline and aortic stiffness and pulse pressure, suspected previously on mechanistic grounds,2 has been confirmed by Waldstein et al3 for the Baltimore …
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