Brain metastassis from lung carcinome

Abstract

Lung cancer is one of the leading causes of cancer-related death worldwide. Brain metastasis is a common person in patients with advanced lung cancer, which can affect the quality of life and survival of patients. This condition may be asymptomatic at first, but eventually it can cause symptoms such as headache, vision changes, balance and cognition problems. Treatment requires an individualized approach with multidisciplinary strategies with the main objective of controlling both the primary tumor in the lung and the air metastases, to provide the best possible clinical outcome for patients. Therapeutic options may include a combination of modalities such as surgery, radiotherapy, chemotherapy, molecular therapy, and immunotherapy. Molecular therapy and immunotherapy have flourished as promising options for patients with lung cancer with brain metastases, being thought of in conjunction with other treatment modalities to maximize clinical outcomes. The following report addresses a 66-year-old patient who presented with progressive hemiparesis in the left side of the body. Examinations revealed an expanding right frontal lesion with edema. Surgery was performed to remove the intracranial tumor, with satisfactory evolution. Histopathological examination indicated metastatic adenocarcinoma of pulmonary origin. After initiation of chemotherapy, drug-induced hepatitis developed due to phenytoin intoxication, but recovered after drug withdrawal. He is currently undergoing ongoing treatment for lung cancer and is being followed up on an outpatient basis.