Abstract
In the previous paper, we showed that there is an increased incorporation of uridine into polysomes of brain during a 15-minute avoidance training experience.1 Although the most obvious difference between the trained and yoked animals in this experiment is that one mouse learns to avoid shock, there are many other differences that have to be considered: Locomotion, attention, performance, stress, change in cue, and the presence of the shelf are but a few of these. We have now carried out experiments to identify or eliminate certaini aspects of the experiences and responses that may be causes of the alterations in RNA metabolism that we have reported. Thus, as an extension of this work, we have studied the effect of different traininig and behavioral experiences on the incorporation of uridine inito polysomes of mouse brain.
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