Abstract

目的 探讨伴有与不伴有学习障碍(LD)注意缺陷多动障碍(ADHD)患儿功能磁共振成像(fMRI)的异同.方法 使用超导型磁共振仪,对19名健康儿童,17例ADHD患儿及10例合并LD的ADHD患儿进行视觉注意作业的fMRI检查.结果 (1)与正常儿童相比,ADHD组显示双侧前额叶(左额上回:正常儿童组15/4,ADHD组6/11,P<0.05;右额上回:正常儿童者组16/3,ADHD组5/12,P<0.01)、右额中回(正常儿童组16/3,ADHD组8/9,P<0.05)以及左额下回(正常儿童组15/4,ADHD组5/12,P<0.01)功能低下.(2)伴有LD的ADHD组在右侧扣带回(3/7)激活脑区计数低于ADHD组(13/4),差异有显著性(P<0.05).结论 伴有LD的ADHD右侧扣带回受损更明显,其余fMRI模式与ADHD组相似。

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