Abstract
Substrate properties of brain cholinesterases were studied in ringed seal and beluga. Kinetic parameters of hydrolysis of thiocholine esters of carboxylic acids were determined. According to the substrate specificity, the enzyme from the brain of marine mammals can be assigned to acetylcholinesterases. Specific properties of the enzyme from the brain of marine mammals were demonstrated in comparison with land animals. The revealed differences in kinetic parameters of the brain enzyme activity are considered in terms of different biochemical adaptation in ringed seal and beluga.
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