Abstract
Compromise in cognitive function in patients with carotid bifurcation disease is well documented. This might result from hypoperfusion of the affected hemisphere. However, not every patient with asymptomatic high-grade carotid stenosis will have compromised blood flow because collateral blood flow, via the circle of Willis, might provide adequate compensation. In their previous reports, Lal et al1 and Gray et al2 showed a clear correlation between carotid stenosis and impaired cognitive function but did not provide a mechanism.
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