Abstract
Summary: Brain is a Java software library facilitating the manipulation and creation of ontologies and knowledge bases represented with the Web Ontology Language (OWL).Availability and implementation: The Java source code and the library are freely available at https://github.com/loopasam/Brain and on the Maven Central repository (GroupId: uk.ac.ebi.brain). The documentation is available at https://github.com/loopasam/Brain/wiki.Contact: croset@ebi.ac.ukSupplementary information: Supplementary data are available at Bioinformatics online.
Highlights
Drug repurposing is the application of known drugs to new indications
Brain is a Java software library facilitating the manipulation and creation of ontologies and knowledge bases represented with the Web Ontology Language (OWL)
Brain aims at filling the gap between the OWL-API and Protege, and is useful to perform biomedical analysis based on description logics
Summary
Drug repurposing is the application of known drugs to new indications. Various computational methods have been recently developed in order to predict such opportunities, based on data coming from gene expression experiments to chemical structure analysis for example. Brain is a Java software library facilitating the manipulation and creation of ontologies and knowledge bases represented with the Web Ontology Language (OWL). The library focuses on the OWL2 EL profile, which enables the use of fast and parallel reasoner such as ELK.
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