Brain activity associated with skilled finger movements: Multichannel magnetic recordings

Abstract

We recorded with a 24-channel SQUID magnetometer cerebral activity preceding and following self-paced voluntary 'skilled' movements in four healthy adults. The subject pressed buttons successively with the right index and middle fingers aiming at a time difference of 40-60 ms; on-line feedback on performance was given after each movement. Slow magnetic readiness fields (RFs) preceded the movements by 0.5 s and culminated about 20 ms after the electromyogram (EMG) onset. Movement-evoked fields, MEFs, opposite in polarity to RFs, were observed 90-120 ms after the EMG onset. They were followed by an additional 'skilled-performance field', SPF, 400-500 ms after the EMG onset. The source locations of RF, MEF, and SPF were within 2 cm from sources of the somatosensory evoked responses, which were situated in the posterior wall of the Rolandic fissure; the sources of MEF were closest to the midline. Neural generators of these deflections and of the corresponding electric potentials are discussed.