Bradypsychia and Urinary Incontinence Secondary to Frontal-Lobe High Grade Astrocytoma

Abstract

Background: Lower urinary tract symptoms (LUTS) are complaints that characterized by two symptoms, an overreactive symptoms such as frequency and urgency, and outlet obstruction symptoms such as difficulty urinating and weak urinary flow. Neurologic diseases such as diabetes mellitus are well-known causes of LUTS, however LUTS secondary to an intracranial mass lesion has been very rarely described in the literature. Case Report: 52-year-old woman came to Neurology outpatient clinic with difficulty in communicating. The patient's family said that the patient often did not connect to talk for approximately 3 months. Patients also often wet in the bed in the last 1 month. CT Scan with contrast revealed intracranial lesions in the right frontal lobe and diffuse brain edema, most likely high-grade astrocytoma Discussion: Lower urinary tract symptoms (LUTS) are very common in men. There are many causes of LUTS, such as neurologic, anatomic, inflammatory, infection, psychogenic, and idiopatic. Intracranial tumors rarely cause LUTS, but the pathophysiology is clearly known. Andrew and Nathan were the first researchers to report a frequency, urgency, and urinary incontinence syndrome that caused mass in the frontal lobe and anteromedial parts of the frontal lobes including the cingulate girus in 1964. Maurice-Williams also reported a serial case in which 7 of 50 patients with tumors the frontal lobe is associated with LUTS. Conclusion: Frontal lobe mass are an uncommon cause of LUTS. If the person with LUTS has no known cause, then the neurological cause must be considered. Symptoms such as bradypsychia (slowness of thought or mental activity), decreased motivation, and intracranial mass symptoms must be considered in order to determine the cause of LUTS.