Abstract
The introduction of interstitial radiation sources is the «youngest» of the radical method of treatment of patients with prostate cancer (PC). The high level of efficiency comparable to prostatectomy at a significantly lower rate of complications causes rapid growth of clinical use of brachytherapy (BT). Depending on the radiation source and the mode of administration into the prostate gland are two types BT – high-dose rate (temporary) (HDR-BT) and low-dose rate (permanent) (LDR-BT) brachytherapy. At the heart of these two methods are based on a single principle of direct effect of the quantum gamma radiation on the area of interest. However, the differences between the characteristics of isotopes used and technical aspects of the techniques cause the difference in performance and complication rates for expression HDR-BT and LDR-BT.
Highlights
The introduction of interstitial radiation sources is the «youngest» of the radical method of treatment of patients with prostate cancer (PC)
At the heart of these two methods are based on a single principle of direct effect of the quantum gamma radiation on the area of interest
The differences between the characteristics of isotopes used and technical aspects of the techniques cause the difference in performance and complication rates for expression HDR-BT and LDR-BT
Summary
The introduction of interstitial radiation sources is the «youngest» of the radical method of treatment of patients with prostate cancer (PC). Рассматривая показания для применения ВДБТ при лечении РПЖ необходимо помнить, что первоначально этот метод разрабатывался в качестве метода подведения дополнительной дозы излучения – boost Среди методов БТ больных РПЖ наибольшее распространение получила НДБТ, которая заключается в однократном введении в ПЖ изотопов с относительно невысокой энергией излучения и периодом полураспада от 9 до 60 дней.
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