Brachial plexopathy following high-dose melphalan and autologous peripheral blood stem cell transplantation

Abstract

Neuromuscular pathologies are a recognized complication of SCT, often occurring as a result of infection or haemorrhage, but also in association with GVHD following allogeneic SCT.1 The published literature on post-transplant peripheral nervous system pathologies includes descriptions of myasthenia gravis, Guillain-Barre syndrome, polymyositis and peripheral neuropathy.2, 3, 4, 5 Ocular toxicity, radiculopathy and plexopathy have also rarely been reported. We report three cases of brachial plexopathy occurring after autologous peripheral blood stem cell transplantation (PBSCT).