Abstract
The present study aims at assessing Bisphenol A (BPA) level in water used in laboratories. A total of five types of water commonly used in laboratory (tap, softened, distilled, double distilled, commercial LC-MS pure water), were analyzed and BPA was quantified by liquid chromatography-tandem mass spectrometry (LC-MS/MS). Only the samples of ultrapure water showed BPA levels above detection limits (>0.004 ng/mL). The mean BPA level ranged from 0.008 to 0.473 ng/mL. A higher mean BPA level was found in water obtained from ultrafilter process compared to commercial sources. Activated carbon filtration is necessary to achieve a BPA free level in ultrapure water.
Highlights
Bisphenol A (BPA) is an endocrine-disrupting chemical (EDC) used in the production of plastic food and beverage containers, leading to ubiquitous low-dose human exposure
The present study aims at assessing Bisphenol A (BPA) level in water used in laboratories
Aim of this paper is to provide data to minimize accidental BPA exposure by analyzing the water commonly used in laboratories
Summary
Bisphenol A (BPA) is an endocrine-disrupting chemical (EDC) used in the production of plastic food and beverage containers, leading to ubiquitous low-dose human exposure. It has been suggested that this exposure to low doses of BPA may be associated with increased susceptibility to reproductive and neurobehavioral disorders, heart disease, type 2 diabetes, prostate and breast cancer, and many other diseases [1,2,3,4,5]. These potential adverse health effects have been assessed by several studies performed in rodent models for the purpose of extrapolating data to humans [6,7]. To have previously developed and optimized a method for the extraction, purification and analysis of BPA has allowed a rapid screening of samples from different purification system and repeatedly sampled in time
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