Abstract
The term dyskeratosis, as defined by Darier, 1 represents a faulty development of epidermis in course of which a certain number of malpighian cells become isolated and differentiated from their fellows, undergoing an abnormal, premature and imperfect keratinization. These dyskeratotic cells are present in layers of epidermis, as far as in horny layer, in form of 'round bodies' (corps ronds), granules (grains), globes or corpuscles, with or without nuclei, easily distinguished from still normal cells as well as from parakeratotic cells. In 1914, Darier 1 designated a group of dermatoses under general heading of the dyskeratoses. The classification was based on assumption that primary and characteristic histologic feature of lesion in these diseases was dyskeratosis. The diseases classified as belonging to group are: Bowen's precancerous dermatosis. Paget's disease of nipple. Dyskeratosis follicularis (Darier's disease). Dyskeratosis follicularis (Darier's disease). Molluscum contagiosum.
Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
