Abstract
Bowen's disease is an intraepidermal carcinoma that can progress to invasive carcinoma and can affect several organs, including the vulva. This clinical case presents a 45-year-old patient with vulvar BOWEN'S disease, with hyperpigmented, dyschromic vulvar and anal exophytic lesions on the clinical examination. The Skin and vulvar biopsy showed a squamous cell carcinoma in situ with no invasive sites. Cytological sampling of ASC-H cervix, showed at colposcopy: endocervical TAG2A, ZT3. The nail biopsy showed a squamous cell carcinoma in situ (Bowen's disease) with no signs of invasion. The patient was operated for a conization, and the histological examination revealed a squamous cell carcinoma in situ with microinvasive focus 3mm wide and 2mm deep with upper tumour border. Therefore, a total vulvectomy with hysterectomy without adnexal preservation was performed. The aim of the current treatment is to have a conservative approach, and to preserve the anatomical and functional integrity of the vulva as far as possible.
Published Version
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