Abstract
Bovine tuberculosis (bTB), caused by Mycobacterium bovis, is an important zoonotic disease with global distribution. While M. bovis is inherently resistant to pyrazinamide, human cases of infection with M. bovis might experience serious cure failures if no correct identification of the pathogen is achieved.Bovine TB was initially reported in Iran by a French veterinarian in local breeds of cattle. An official attempt to control the disease was started in the 1940s, which runs today on a national scale. This mini-review addresses a variety of different epidemiological issues in bTb control in the world and in Iran from an immunologist’s eye to find the cure for human cases infected with M. bovis. In addition, the benefits and drawbacks of this control scheme are discussed.
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