Abstract
Thus far, histotripsy has not successfully fractionated tendon tissues, possibly due to bubbles being of insufficient size to create a pressure-release interface. In this study, a planar tissue-air interface was treated with histotripsy to create a micro-fountain and atomization; particulates ejected from the tendon sample were collected and analyzed histologically to determine whether tissue fractionation was achieved. [Work supported by NSF GRFP DGE1255832 and NIH NIBIB EB027886.]
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