Abstract
Our results demonstrate that immunizationwith LAM is able to inducea specifichumoral immuneresponsewithout interfering with IDR test usually used for bovine Tuberculosis diagnosis. It has been described that IgG1 is the predominant isotype in the immune response to LAM of infected animals Koets et al. (2001). Our results indicate that the same isotype profile is obtainedwhen LAM is inoculated as a purified antigen. These results could support further investigations evaluating LAM as a candidate for a Paratuberculosis subunit vaccine.
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