Boundary Element Discretization in Realistic Volume Conductor Modeling in Fetal Magnetoencephalography

Abstract

Event Abstract Back to Event Boundary Element Discretization in Realistic Volume Conductor Modeling in Fetal Magnetoencephalography Jens Haueisen1*, Roland Eichardt2, Uwe Schneider3 and Ekkehard Schleussner3 1 Technical University Ilmenau, Germany 2 University Hospital Jena, Germany 3 Friedrich Schiller University Jena, University Hospital, Dept. of Obstetrics,, Germany Source reconstruction in fetal Magnetoencephalography (fMEG) has a high potential to become a valuable tool for both basic and clinical research in developmental neurology. However, volume conductor modeling, which is an important prerequisite for source reconstruction, has not been sufficiently addressed so far. In this paper, we investigate the influence of the boundary element discretization on the simulated fMEG. We construct realistic volume conductor models based on 3D ultrasound images. Two different models are considered: a three compartment model including the fetal head, the vernix caseosa, and the maternal abdomen and a three compartment model including the entire fetus, the vernix caseosa, and the maternal abdomen. The boundary element discretization is varied between 20 mm and 12 mm triangle side length for the maternal abdomen, between 7 mm and 2 mm for the vernix caseosa, and between 7 mm and 2 mm for the fetus or the fetal head. The computed magnetic fields caused by dipolar sources positioned in the different models with different discretizations are compared with the help of the magnitude factor and the correlation coefficient. In line with our earlier investigation we find high differences in the computed amplitudes (minimum MAG of 0.47) between the two models for all BEM discretizations, while at the same time the correlation coefficients are above 0.95. This indicates that the entire fetus needs to be considered in the modeling approach. Comparing the different BEM discretizations, we obtain that the largest difference between the coarsest model (20, 7, 7 mm) and the finest model (12, 2, 2 mm) is 26 % in magnitude and the correlation is 0.97. Magnitude differences of less than 6 % and correlation coefficients higher than 0.99 are obtained for a BEM discretization of 16 mm for the abdomen, 5 mm for the vernix caseosa and the fetus. Our simulations provide a first guideline for the construction of boundary element models in fMEG source reconstruction procedures. Conference: Biomag 2010 - 17th International Conference on Biomagnetism , Dubrovnik, Croatia, 28 Mar - 1 Apr, 2010. Presentation Type: Oral Presentation Topic: Fetal and neonatal biomagnetism Citation: Haueisen J, Eichardt R, Schneider U and Schleussner E (2010). Boundary Element Discretization in Realistic Volume Conductor Modeling in Fetal Magnetoencephalography. Front. Neurosci. Conference Abstract: Biomag 2010 - 17th International Conference on Biomagnetism . doi: 10.3389/conf.fnins.2010.06.00092 Copyright: The abstracts in this collection have not been subject to any Frontiers peer review or checks, and are not endorsed by Frontiers. They are made available through the Frontiers publishing platform as a service to conference organizers and presenters. The copyright in the individual abstracts is owned by the author of each abstract or his/her employer unless otherwise stated. Each abstract, as well as the collection of abstracts, are published under a Creative Commons CC-BY 4.0 (attribution) licence (https://creativecommons.org/licenses/by/4.0/) and may thus be reproduced, translated, adapted and be the subject of derivative works provided the authors and Frontiers are attributed. For Frontiers’ terms and conditions please see https://www.frontiersin.org/legal/terms-and-conditions. Received: 23 Mar 2010; Published Online: 23 Mar 2010. * Correspondence: Jens Haueisen, Technical University Ilmenau, Ilmenau, Germany, jens.haueisen@tu-ilmenau.de Login Required This action requires you to be registered with Frontiers and logged in. To register or login click here. Abstract Info Abstract The Authors in Frontiers Jens Haueisen Roland Eichardt Uwe Schneider Ekkehard Schleussner Google Jens Haueisen Roland Eichardt Uwe Schneider Ekkehard Schleussner Google Scholar Jens Haueisen Roland Eichardt Uwe Schneider Ekkehard Schleussner PubMed Jens Haueisen Roland Eichardt Uwe Schneider Ekkehard Schleussner Related Article in Frontiers Google Scholar PubMed Abstract Close Back to top Javascript is disabled. Please enable Javascript in your browser settings in order to see all the content on this page.