Botulinum Toxin in the Management of Hyperhidrosis and Other Salivary Conditions

Abstract

The aim of this review is to summarise the most up-to-date literature on the application of botulinum toxin in hyperhidrosis and other salivary conditions, including sialorrhea, salivary leak and Frey’s syndrome. Surgeons performing this procedure should stay updated with the most recent evidence of its effectiveness for appropriate treatment planning and patient consultation. The use of botulinum toxin in hyperhidrosis provides symptom relief in most patients, with satisfaction rates of 80–100% in the majority of patients. Accidental infiltration of local musculature is the most common complication, providing a transient paralysis which is reversible. There has been an increasing body of evidence on the effectiveness of botulinum toxin in salivary gland conditions. This has been able to confirm and quantify its utility as a temporary symptom relief treatment, with minimal complications. For both conditions examined, there is a lack of literature comparing the effect of botulinum toxin to other treatment modalities. Botulinum toxin has a growing body of evidence in hyperhidrosis and other salivary conditions. Overall, it is a very safe treatment which provides symptom relief and increased patient satisfaction in most patients. During consultations, surgeons should highlight the need of recurrent applications and the risk of diminishing efficacy with continuous use.