Abstract
Attempting to ride on the coattails of botulinum toxin type A (Botox), manufacturers of several cosmeceuticals claim similar or even better efficacy. In this study sponsored by the manufacturer of Botox, 77 women randomly received Botox, placebo, or one of three topical creams for their moderate-to-severe glabellar rhytids. The studied agents were Botox, 20 units total; StriVectin-SD twice daily for 12 weeks; Wrinkle Relax (formerly Faux-Tox) twice daily for 12 weeks; HydroDerm twice daily for 12 weeks; and sterile saline injections. Glabellar wrinkle severity at rest …
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