Abstract

The international debate on animal testing, its improvement through the well known "3Rs" methodology, and the possibility of its replacement with the emergent NATs (Non-Animal Technologies) brought into the new millennium a turn. Nations as U.S.A. and U.K., and partly international bodies as the EU. seem be doing a renewed effort to diminish and possibly replace animal testing with more reliable and less invasive techniques, to which also the giants of the chemical and pharmaceutical industry seem very interested.

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