BOS-technologies of rehabilitation in patients with Parkinsonism

Abstract

Parkinsonism is progressive neurodegenerative pathology. It is subdivided on Parkinson’s diseases (PD) and syndrome of parkinsonism (PS). Mobile biofeedback-brain stimulation is one of new technologies of rehabilitation in neurology. Assessment tools:MoСa-test, HADS, UPDRS, Hoehn-Yahr Scale, Vegetative disturbance Scale, SF-36. 150 patients were included this trial: PD – 112, PS – 38. All groups were divided into 2 subgroups: 1) therapy with BOS-brain stimulation; 2) therapy without stimulation. Sensory-motor processes of finger tapping were accessed by special mobile application installed on smartphone. Stimulation programs were prescribed for patients as a sound stimulus by headset in individual regimes during 14-20 days twice per day. PD group: 63,4% of patients had akinetic-rigid-tremor syndrome as motor dysfunction, 32,1% had mild cognitive impairments, 35,7% - anxiety, 33% – depression. PS group: 36,8% of patients had akinetic-rigid syndrome as motor dysfunction, 50% had mild cognitive impairments, 39,5% – subclinical depression. Best results of BOS-stimulation were revealed in PD group. it was evidenced by MoCa-test (р<0,0001), HADS anxiety index (р<0,0001), HADS depression index, SF-36 (р<0,0001). Results of BOS-stimulation in PS group evidenced by MoCa-test, HADS anxiety index, HADS depression index. Obtained data reveal that most frequent type of Parkinson’s disease was akinetic-rigid-tremor, non-motor symptoms were presented by mild cognitive impairments, anxiety, depression. In group of syndrome of parkinsonism most frequent type was akinetic-rigid, non-motor symptoms were presented by mild cognitive impairments and subclinical depression.