Abstract
e172 sessions. Thirteen (19.7%) patients were poor mobilizers. These patients had delay in neutrophil engraftment (p1⁄40.0004), platelet engraftment (p1⁄40.0002), had more platelet transfusion requirement (p1⁄40.03) and prolonged hospitalization (p1⁄40.02) compared to patients who were transplanted with stem cell dose of >3 10 cells/ kg. Univariate and step wise multiple regression was done to determine the factors predictive of poor mobilization (table 1). Receiver Operating Charecteristics (ROC) analysis to find out the cut-off of d4-PBCD34+ which was predictive of poor yield with 93% sensitivity and 77% specificity is 25/mL, with an AUROC of 0.89 (figure 1). Conclusion: Age >50 years, marrow involvement with disease prior to mobilization and a d4-PBCD34+ of 20/mL were significant predictors of poor mobilization in present study. A d4-PBCD34+ of <25/mL predicts a poor yield with reasonable accuracy. These patients would benefit from alternate/rescue strategies at mobilization.
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