Abstract

AbstractAn atom‐economical synthesis of 3‐alkylidene‐3H‐indole N‐oxides has been developed via a tandem reaction of propargylic alcohols and nitrosobenzenes in the presence of boron trifluoride etherate (BF3⋅Et2O) as catalyst. This method offers great potential for the synthesis of biologically important 3‐alkylidene‐3H‐indole N‐oxides and related derivatives.magnified image

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