Abstract
<i>Bordetella pertussis</i>in Adult Pneumonia Patients1
Highlights
Serum samples taken from the patients during acute and convalescent phases of disease were tested for immunoglobulin (Ig)A and IgG antibodies against B. pertussis whole cell antigens by using enzyme-linked immunosorbent assay (ELISA) (Pan Bio, Queensland, Australia)
All positive serum samples were tested for pertussis toxin (PT) IgG antibodies, the most specific serologic marker for recent B. pertussis infection [5]
We found evidence of recent B. pertussis infection in 3% of adults admitted to the hospital with well-defined pneumonia during a period of increased pertussis activity, and weaker evidence in an additional 6%
Summary
BALB/c and C57BL/6 mice infected with virulent Burkholderia pseudomallei provide contrasting animal models for the acute and chronic forms of human melioidosis. This study searched for evidence of B. pertussis infection in 304 adults (≥18 years) admitted to Christchurch Hospital (Christchurch, New Zealand) with communityacquired pneumonia from August 1999 to July 2000 [3]. Nasopharyngeal samples and paired serum samples from these patients were stored and later tested for B. pertussis DNA and B. pertussis antibodies.
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