Abstract

To the Editor: We congratulate Yong and colleagues on their recent article about borderzone infarction.1 However, the findings from this detailed study can be interpreted differently and we would like to propose an alternative conclusion. Originally, the interest in these stroke syndromes was that their recognition potentially suggested a hemodynamic mechanism and hence direction for medical therapy.2 Investigators emphasized the importance of severe carotid artery stenosis/occlusion coupled with hemodynamic compromise to the mechanism of internal borderzone (IBZ) infarction.3,4 However, this is not a constant finding, and others have found IBZ infarction occurring in the setting of mild, moderate and severe carotid artery stenosis.5 The cortical borderzone (CBZ) hypothesis was also questioned when it was …

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