Abstract
Objective: to have an analgesic effect, to improve spinal mobility, and to maintain adequate bone mineral density (BMD) in patients with osteoporosis (OP) treated with Bora Bora that has a combined effect on bone tissue. Subjects and methods. Fifteen patients (mean age 63,7+8,4 years) with OP were treated with Bora Bora as a capsule 4 times daily for 6 months. During Bora Bora treatment, another therapy for OP was not performed. The intermittent use of nonsteroidal anti-inflammatory drugs (NSAIDs) was allowed in severe pains. The patients underwent a routine clinical laboratory examination; dual-energy X-ray absorptiometry (DEXA) was used to estimate BMD; the authors determined the intensity of pain in the back and on palpation of paravertebral muscles by the VAS (visual analog scale (in mm), the range of spinal motions, the overall efficiency of treatment, and the presence of adverse reactions. Examinations were made on the day of treatment initiation, following 2 weeks, and at months 1, 2, 3, and 6 of Bora Bora therapy. Results. Increased BMD was noted in all the patients after treatment with Bora Bora (according to the data of DEXA). The effect depended on the timeliness of using the drug. The rate of BMD increase in the lumbar vertebrae was 0,5-2% higher than that in the femoral neck in 50- 70-year-old women. After 70 years of age, the rate of a bone mass increment was much less, particularly in the femoral neck. Conclusion. When Bora Bora was given, there was pain relief and increases in the range of vertebral motions and BMD. Bora Bora was shown to be well tolerated by and to be beneficial to patients with OP.
Highlights
Training-Research Medical Center, RF President’s Administration of Affairs, Central Clinical Hospital with a Polyclinic, RF President’s Administration of Affairs, Moscow
Objective: to have an analgesic effect, to improve spinal mobility, and to maintain adequate bone mineral density (BMD) in patients with osteoporosis (OP) treated with Bora Bora that has a combined effect on bone tissue
Fifteen patients with OP were treated with Bora Bora as a capsule 4 times daily for 6 months
Summary
Учебно-научный медицинский центр Управления делами Президента РФ, ЦКБ с поликлиникой Управления делами Президента РФ, Москва. Цель исследования – получить обезболивающий эффект, улучшение подвижности в спине и сохранить достаточную минеральную плотность костной ткани (МПК) у пациенток с остеопорозом (ОП) на фоне лечения препаратом Бора Бора, комплексно воздействующим на костную ткань. Больным проводили стандартное клинико-лабораторное обследование, оценивали МПК методом двухэнергетической рентгеновской абсорбциометрии (ДРА), выраженность боли в спине и при пальпации паравертебральных мышц по ВАШ (в мм), объем движений в позвоночнике, общую эффективность лечения, побочные явления. Предрасполагающими к переломам, являются снижение массы и минеральной плотности кости (МПК), а также изменения качества кости, характеризующиеся нарушением геометрии костей, особенно шейки бедра, и микроархитектоники трабекул костной ткани. Бора Бора улучшает метаболизм костной ткани, оказывает противовоспалительное и анальгетическое действие, что позволяет рассчитывать на его высокую клиническую эффективность при ОП. В процессе лечения Бора Бора боль в спине по ВАШ уменьшилась с 61,7±11,2 до 49,2±21,6 мм (рис. 1), боль при пальпации паравертебральных мышц по ВАШ – с 60,4±15,0 до 44,9±17,7 мм (рис. 2)
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