Abstract

Cardiac surgery is associated with tremendous release of endogenous stress hormones and catecholamines resulting in increase in right ventricular (RV) dysfunction. High spinal anaesthesia (HSA) has been shown to attenuate stress response, reduce release of inflammatory mediators, prevent β receptor down regulation and improve left ventricular function.1 RV function play very important role in the outcome of patients after mitral valve surgery. We hypothesized that HAS may improve RV function in patients with pulmonary arterial hypertension (PAH) secondary to mitral valve disease.

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