Abstract

This book has been published to present in great detail the recent advances of yeast metabolic engineering, with a special focus on tools, technologies, assays, pathway engineering, selection, optimization, and screening. This book is written in an easy to understand language by eminent scientists in the field of metabolic engineering. It is a timely compilation of the recent advances and the future scope of the field. This book is an excellent and informative for yeast metabolic engineering experiments, as the editor has made an impressive compilation of almost of all the methods for the manipulation of yeast strains, and the consequent development of strains for industrial purposes with great simplicity. The central idea behind the book is to highlight the number of important aspects of metabolic engineering in a way that can help future investigators, researchers, students, and stakeholders to perform research with ease.

Highlights

  • Synthetic Biology Laboratory, Department of Microbiology, School of Biological Sciences and Biotechnology, Institute of Advanced Research, Gandhinagar, India

  • Recent advances in the yeast molecular biology toolbox and the access to the complete genome sequencing data of yeast Saccharomyces cerevisiae has opened up new avenues for greater understanding of the yeast physiology, metabolism and has driven the acceleration of its metabolic engineering

  • Yeast research has been boosted and its perspectives have been further augmented by the creation of a synthetic yeast cell of S. cerevisiae with a highly modified genome that has reduced (8%) by size (Richardson et al, 2017)

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Summary

Introduction

A book review on Yeast Metabolic Engineering: Methods and Protocols by Mapelli, V. These yeast cell factories can be engineered using metabolic engineering through the use of systems and synthetic biology principles and by following iterative step wise operation starting from an in silico design, followed by construction and the analysis of final variants with the ability to produce desired molecules (Kim et al, 2012).

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