Bone tissue reactions to periodontal dressings.

Abstract

78 rats weighing 180–200 g were used to assess the bone tissue responses to three periodontal dressings (Coe‐pak, Peripac and Ward's Wondrpak). The dressings were implanted subscutaneously on periosteal covered and denuded bone. Sham operated animals served as controls and a comparison btween the responses produced by the three dressngs were made.In one series the dressings remained in situ for 3, 7, 14, 30 and 90 days. Osteocyte damage of varying extent was recorded for all materials. Remodelling of the bone surface adjacent to the dressing was observed. Bone resorption was never foud in the gournd defect produced to denude the bone tissue, but repair of the defect by bone formation was observed after long observation periods. This repair was retarded in some animals were Ward's Wondrpak had been implanted.In another seiries Ward's Waondrpak was implanted against bone for three days, then re‐operated to remove the dressing and the defect allowed to heal for 30 days. The test group exhibited empty bone lacunae and the repair of the defect was retarded or lacking.