Abstract
03Dec 2018 BONE SUBSTITUTE VERSUSSTEM CELLS IN REGENERATION OF ALVEOLAR BONE DEFECTS IN HUMANS: SYSTEMATIC REVIEW. Abeer Kamal , Walaa Aboelalaa and Mushira Dahaba. Associate prof. Oral and Maxillofacial Surgery, College of Oral and Dental Surgery, Misr University for Science and Technology, Giza, Egypt. Lecturer of Oral and Maxillofacial Radiology, Faculty of Oral and Dental Medicine, Beni-seuf University,Beni-suef, Egypt. Professor of Oral and Maxillofacial Radiology, Faculty of Dentistry, Cairo University, Cairo, Egypt.
Highlights
Healing of alveolar bone defect in humans is considered a major problem in oral and maxillofacial area
Stem cells being a new technique that evolved in past years was used to close defective areas
No strong and solid evidence to support the difference between two interventions in regeneration of alveolar bone defects in humans
Summary
No strong and solid evidence to support the difference between two interventions in regeneration of alveolar bone defects in humans. Different types of stem cells represent a potential key component in autologous graft for bone regeneration.In contrast, bone substitute materials that were commonly used for reconstruction of alveolar bone defect including autogenous bone graft, allograft, xenograftand synthetic bone materials. The aim of the present investigation was to systematically review and assess all relevant literature concerning the regeneration of alveolar bone defect using bone substitute versus stem cell in humans. Selection criteria: Allrandomized controlled clinical trial (RCT) assessing stem cells and bone substitute in regeneration of alveolar bone defects were included. (d) Clinical advantages afforded by the grafting of autologous DPSCs more significant than the disadvantages arising from regeneration of a bone type that is not normally present in the area treated. Table 2:-Summary of the excluded studies and the reason for their exclusion: References
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