Abstract
Bone scintigraphy with 99m-Tc HMDP was investigated for its pathological basis in a patient with mucoepidermoid carcinoma in the right molar region of the mandible. An accumulation of 99m-Tc HMDP was remarkable in the bone surrounding the tumor. There were large numbers of osteoblasts and a large increase in the amount of osteoid tissue which lined most of the surface of the immature woven bone. The result of our investigation suggested that the concentration of 99m-Tc HMDP was not tumor specific in itself and mostly depend on production of reactive immature new bone. The bone scintigraphic finding was necessary to be interpreted according to the pathological basis.
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