Abstract
The aim was to evaluate the bone response to machined cast titanium (Ti) implants. Commercially pure (c.p.) machined Ti implants served as controls. Analyses of the surface composition and topography by Auger electron spectroscopy (AES) and scanning electron microscopy (SEM) revealed no differences comparing the two materials. Cast screw-shaped and identical machined Ti implants were inserted in the tibial metaphysis of 6 rabbits. After 3 and 6 months, the amount of bone within threads and the degree of bone-implant contact were histomorphometrically evaluated. The bone area of cast Ti implants was 45% after 3 months and 62% after 6 months. The corresponding values for machined Ti implants were 51% and 58%, respectively. The total bone-implant contact for cast Ti implants was 19% (25% control implants) after 3 months and 45% (37% for control implants) 6 months after implantation. No statistically significant differences were observed between the two materials at any time interval. The present experimental results indicate that machined cast Ti implants integrate equally well in bone as machined c.p. Ti implants do.
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