Abstract
Introduction: Osteoporosis is a multifactorial skeletal disease that is characterized by reduced bone mineral density (BMD). BMD values depend on several factors such as age, sex and age at menopause. The purpose of this study was to determine the prevalence and changes in bone mineral density in Iranian patients. Methods: Three hundred patients were selected through random sampling technique in 2009. BMD was assessed by Norland (Excell) technique at the lumbar and femoral neck. Weight and height were measured through standard methods. A thorough history was taken from each patient. The data was analyzed using SPSS software version 13.0. P-values less than 0.05 were considered statistically significant. Results: From among the 300 studied patients, 86.6% were female. their mean age was 52.7 years. Their average body mass index (BMI) was 28.14 kg/m2. Mean T-Score at lumbar spine and femoral neck was -1.07 ±1.19 and -1.75 ± 1.33 respectively. Mean BMD value at lumbar spine and femoral neck was 0.92 ± 0.19 and 0.77 ± 0.16 respectively. The prevalence of osteoporosis at lumbar spine and femoral neck was 33.7% and 16.7, respectively. There was a significant correlation between age, BMI and BMD values (P-Value Conclusion: This study shows that ageing and low BMI are risk factors associated with bone loss. it is recommended to measure BMD and implement prevention programs for high-risk people.
Highlights
Osteoporosis is a multifactorial skeletal disease that is characterized by reduced bone mineral density (BMD)
Osteoporosis is a multifactorial skeletal disease characterized by reduced bone mineral density (BMD) along with the deterioration of the microarchitectural structure of bone tissue, and a consequent increase in bone fragility and fracture risk [1,2]
Regarding the values reported at the femoral neck, 50 patients (16.7%) had osteoporosis and 121 others (40.3%) had osteopenia
Summary
Osteoporosis is a multifactorial skeletal disease that is characterized by reduced bone mineral density (BMD). Mean T-Score at lumbar spine and femoral neck was −1.07 ± 1.19 and −1.75 ± 1.33 respectively. Mean BMD value at lumbar spine and femoral neck was 0.92 ± 0.19 and 0.77 ± 0.16 respectively. The prevalence of osteoporosis at lumbar spine and femoral neck was 33.7% and 16.7, respectively. Correlation between gender and BMD value at the lumbar spine and femoral neck was not significant. Conclusion: This study shows that ageing and low BMI are risk factors associated with bone loss. Osteoporosis is a multifactorial skeletal disease characterized by reduced bone mineral density (BMD) along with the deterioration of the microarchitectural structure of bone tissue, and a consequent increase in bone fragility and fracture risk [1,2]. Osteoporotic fractures affect the quality of life and are associated with premature mortality [14]
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